VITROCELL SYSTEMS: Advanced in vitro exposure systems

Scope of Activities: Systems for Inhalation Toxicology and Percutaneous Penetration

In Vitro Cultivation and Exposure Systems for Inhalation Toxicology

We offer customers from industry and research institutes new culture and exposure systems for in vitro studies of gases or complex mixtures. The VITROCELL® modules offer new possibilities for the characterization of the effects of airborne substances such as:

> Gases
> Complex mixtures
> Nano particles
> Fibres

Application Areas
- Combustion exhaust
- Cosmetics
- Household chemicals
- Indoor / outdoor air analysis
- Industrial chemicals
- Pesticides
- Pharmaceuticals
- Tobacco smoke (whole smoke and gas phase)

Direct Exposure Technology
at the Air / Liquid Interface
Primary cultures and cell lines, e.g. from the respiratory tract, are treated in modules specially designed for direct contact between cells and components of the test atmosphere at the air/liquid interface.

The advantages:

- No loss
- No solution / no dissolution
- No reaction of constituents with medium

The result: High sensitivity of the system

Flow principle video download (3.3 MB wmv)

Please visit the System elements section for a typical system flow chart >> direct link

VITROCELL^® Cultivation and Exposure Modules
	For cultivation and direct exposure of cells or bacteria. There is a wide range of modules engineered for normal to high througput. >> direct link

Complete Exposure Systems including Aerosol Generators
	Turn-key systems including aerosol generators for substances in liquid or powder form as well as various solutions for dose control. >> direct link

VC 10^® Smoking Machines

VITROCELL^® Smoking Machines are designed to the specific needs in in vitro,
chemical and medical research.
>> direct link

VITROCELL^® Equipment for Dose Control

VITROCELL^® Photometers are designed to perform online measurements of
the particle mass at very low flow rates without particle losses.

VITROCELL^® Quartz Crystal Microbalance sensors enable to measure the particle
deposition online in nanogram/cm².

>> direct link

In Vitro Exposure Sytems for Tissue / Percutaneous Penetration

VITROCELL^®Skin Exposure Systems
	The new VITROCELL^® Skin modules are unique systems for the exposure of tissue to liquids and other compounds as well as for the analysis of volatiles. They are available in various sizes and configurations. >> direct link